Back to Search
Start Over
Morphologie des Chiasma opticum bei Albinismus
- Source :
- Der Ophthalmologe. 104:662-665
- Publication Year :
- 2007
- Publisher :
- Springer Science and Business Media LLC, 2007.
-
Abstract
- Albinism is associated with a misrouting of fibers at the optic chiasm where the majority of fibers cross to the contralateral side. The cause of this abnormal decussation pattern reflects a disturbance of cell cycle regulation in the development of the retina which is in part controlled by melanin. Growing axons from retinal ganglion cells therefore arrive later than usual at the optic chiasm and are misrouted contralaterally. This atypical decussation leads to morphological changes of the optic chiasm including a reduced chiasm width with larger angles between optic nerves and tracts which can be shown by magnetic resonance imaging.
Details
- ISSN :
- 14330423 and 0941293X
- Volume :
- 104
- Database :
- OpenAIRE
- Journal :
- Der Ophthalmologe
- Accession number :
- edsair.doi...........40f25238ae14d77e012302c932430808