ChemInform Abstract: Highly Regioselective Functionalization of 2,3-Dialkyl Substituents on Indoles

Authors :: Yoshitaka Ito
Satoshi Inagaki
Yuji Naruse
Source :: ChemInform. 22
Publication Year :: 2010
Publisher :: Wiley, 2010.
Abstract: A novel method for the highly regioselective deprotonation of the indole alkyl substituents has been established by the particular sequence of base treatments. This success may be due to the aromatic stabilization of cross [6e/4p] conjugated systems. We are presently pursuing further application revolving around this methodology

Subjects :: Indole test
chemistry.chemical_classification
Deprotonation
chemistry
Organic chemistry
Surface modification
Regioselectivity
General Medicine
Conjugated system
Combinatorial chemistry
Alkyl

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