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A portable device for in situ deposition of bioproducts

Authors :
Mohan Edirisinghe
Eleanor Stride
Wai K. Lau
Panagiotis Sofokleous
Richard M. Day
Source :
Bioinspired, Biomimetic and Nanobiomaterials. 3:94-105
Publication Year :
2014
Publisher :
Thomas Telford Ltd., 2014.

Abstract

The electrohydrodynamic (EHD) technique has traditionally been confined to the bench-top. Recently, a portable EHD device was constructed that allows the process to be applied in a much more flexible and versatile manner. In this article, the effect of electrode and collector height on the fibers generated by EHD and wound-dressing forming capabilities of the device tested on different types of simulated wound morphologies were investigated. Dressings were also fabricated on living tissue to investigate jet behavior and product morphology. The EHD device was found to be capable of controlled deposition of micrometer-sized poly(D,L-lactide-co-glycolide) acid fibers that can form an opaque, waterproof wound dressing on human skin within a few minutes with excellent adherence.

Details

ISSN :
20459866 and 20459858
Volume :
3
Database :
OpenAIRE
Journal :
Bioinspired, Biomimetic and Nanobiomaterials
Accession number :
edsair.doi...........4079e81c4640775a5227b87516c25d1c
Full Text :
https://doi.org/10.1680/bbn.13.00030