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Light controlled reversible Michael addition of cysteine: a new tool for dynamic site-specific labeling of proteins
Light controlled reversible Michael addition of cysteine: a new tool for dynamic site-specific labeling of proteins
- Source :
- The Analyst. 148:1085-1092
- Publication Year :
- 2023
- Publisher :
- Royal Society of Chemistry (RSC), 2023.
-
Abstract
- An engineered hCRBPII protein binds a coumarin-based fluorophore to yield a photoswitchable system via Michael/retro-Michael addition of a cysteine residue. Alternate UV/visible light irradiation accesses the two optical states.
Details
- ISSN :
- 13645528 and 00032654
- Volume :
- 148
- Database :
- OpenAIRE
- Journal :
- The Analyst
- Accession number :
- edsair.doi...........4075a80940cbd8da8c691be6ed7653cb
- Full Text :
- https://doi.org/10.1039/d2an01395a