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ChemInform Abstract: Access to Drug Metabolites via C-H Functionalization: Copper-Catalyzed Aerobic Oxidation of N,N-Dimethylalkylamines in Complex Pharmaceuticals

Authors :
B. Barry Touré
Dalibor Sames
Julien Genovino
Source :
ChemInform. 46
Publication Year :
2015
Publisher :
Wiley, 2015.

Abstract

The practical, cost-effective and operationally simple two-step transformation is applied to a range of dimethylamine-containing pharmaceuticals including clomipramine (I) and diltiazem (IV).

Details

ISSN :
09317597
Volume :
46
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........40667aeb8195c6ef55cc3e7b4ba0c997