GLIPR1/RTVP-1 tumor suppressor gene expressed by adenovirus vector as neoadjuvant intraprostatic injection for localized high-risk prostate cancer preceding prostatectomy

Authors :: Brian J. Miles
R. K. Jain
Ken-ichi Tabata
Dov Kadmon
Guru Sonpavde
Shinji Kurosaka
Gustavo E. Ayala
Michael Ittmann
Timothy C. Thompson
Kohei Edamura
Source :: Journal of Clinical Oncology. 28:e15026-e15026
Publication Year :: 2010
Publisher :: American Society of Clinical Oncology (ASCO), 2010.
Abstract: e15026 Background: GLIPR1/RTVP-1 is up-regulated by p53 in prostate cancer (PCa) cells and has preclinical pro-apoptotic, anti- angiogenic, immunostimulatory and metastasis-suppressing activity. A ...

Subjects :: Oncology
Cancer Research
medicine.medical_specialty
Tumor suppressor gene
business.industry
Prostatectomy
medicine.medical_treatment
medicine.disease
Viral vector
Prostate cancer
Internal medicine
Medicine
business

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