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Atomic Force Microscopy: A Nanoscopic Application in Molecular and Cell Biology
- Source :
- Atomic Force Microscopy in Molecular and Cell Biology ISBN: 9789811315091
- Publication Year :
- 2018
- Publisher :
- Springer Singapore, 2018.
-
Abstract
- At the prosperous fields of nanoscience and biology, the nanoscale analysis of cells and cell membrane using atomic force microscopy (AFM) is an exciting and rapidly developing research area. Over the past decade, there has been tremendous progress in the use of AFM to observe living cells and membrane proteins at high resolution. Remarkable advances have been made in applying AFM-based force spectroscopy techniques to characterize surface biomechanical properties, to map receptor sites on cell surface, and to measure cellular interactions at the single-cell or single-molecule level. Moreover, recent developments in AFM combining advanced optical microscopy, such as confocal microscopy and near-field scanning optical microscopy, opened up new avenues for cell imaging at nanoscale resolution.
- Subjects :
- Materials science
Atomic force microscopy
Resolution (electron density)
Force spectroscopy
High resolution
Nanotechnology
02 engineering and technology
010402 general chemistry
021001 nanoscience & nanotechnology
01 natural sciences
0104 chemical sciences
law.invention
Cell membrane
medicine.anatomical_structure
Optical microscope
law
Confocal microscopy
medicine
0210 nano-technology
Nanoscopic scale
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Atomic Force Microscopy in Molecular and Cell Biology ISBN: 9789811315091
- Accession number :
- edsair.doi...........3ff8add6228ae2e8913c9b41a300be1d