S36 Differentiation of tuberculosis and sarcoidosis by transcriptional profiling of immune responses in mediastinal lymph node samples

Introduction and Objectives Differentiating tuberculosis and sarcoidosis can be difficult, particularly in the context of mediastinal lymphadenopathy, because both diseases are characterised by overlapping clinical phenotypes and histologically similar granulomatous inflammation. Currently, diagnosis relies heavily on microbiological confirmation of tuberculosis which is only available in