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Differentiation malignant from benign parotid tumors in children with diffusion-weighted MR imaging
- Source :
- Oral Radiology. 37:463-468
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- To differentiate pediatric solid malignant from the benign parotid tumors with diffusion-weighted MR imaging (DWI). A retrospective study comprising 38 children with parotid tumors (21 boys and 17 girls aged from 2 months to 17 years) was conducted using (DWI) of the parotid gland. Apparent diffusion coefficient (ADC) maps were generated. The ADC value of the parotid tumors was calculated. The mean ADC value of malignant parotid tumors (1.08 ± 0.1, 1.04 ± 0.1 × 10−3mm2/s) was significantly lower [P = 0.001] than that of benign lesions (1.69 ± 0.2, 1.72 ± 0.3 × 10−3mm2/s). A threshold of ADC of 1.40, 1.33 × 10−3mm2/s was used for differentiating malignant parotid tumors from benign lesions and led to the best results of the area under the curve of 0.940, 0.929, accuracy of 86, 89%, sensitivity of 94, 94%, specificity of 80, 85%, negative predictive value of 94.1, 94.4%, and positive predictive value of 81, 85%. There was insignificant difference in ADC values of malignant lesions (P = 0.23, 0.30) as well as within benign lesions (P = 0.25, 0.08). DWI is an innovative anticipating imaging technique that can be used in the differentiation of pediatric solid malignant parotid tumors from benign lesions.
- Subjects :
- medicine.medical_specialty
business.industry
Area under the curve
Retrospective cohort study
030206 dentistry
Predictive value
Mr imaging
030218 nuclear medicine & medical imaging
Parotid gland
03 medical and health sciences
0302 clinical medicine
medicine.anatomical_structure
stomatognathic system
Parotid tumors
medicine
Effective diffusion coefficient
Radiology, Nuclear Medicine and imaging
Dentistry (miscellaneous)
Radiology
Diffusion-Weighted MR Imaging
business
Subjects
Details
- ISSN :
- 16139674 and 09116028
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Oral Radiology
- Accession number :
- edsair.doi...........3f79868c66d43cbb13073108006e3a5d
- Full Text :
- https://doi.org/10.1007/s11282-020-00479-2