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A catalyst-free N–H insertion/Mannich-type reaction cascade of α-nitrodiazoesters

Authors :
Lianghui Liu
Xichen Lin
John D. Elliott
Ting Yang
Feng Ren
Hao Zhuang
Jia-Ning Xiang
Source :
Tetrahedron Letters. 54:4159-4163
Publication Year :
2013
Publisher :
Elsevier BV, 2013.

Abstract

A catalyst-free N–H insertion/Mannich-type reaction cascade of α-nitrodiazoesters with anilines has been developed to afford a variety of α-amino-α-aryl esters in 60–83% yields and under mild reaction conditions (23 or 40 °C).

Details

ISSN :
00404039
Volume :
54
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........3f6551c49641d9764d339d81219c80dc
Full Text :
https://doi.org/10.1016/j.tetlet.2013.05.131