Postimplantation Development of the Chorioallantoic Placenta

The chorioallantoic placenta mediates the bidirectional exchange of nutrients, wastes, and gases between mother and baby, performs essential endocrine activities, and participates in the modulation of the maternal immune and vascular systems. It is therefore not surprising that perturbations in placental formation or function may lead to a myriad of pregnancy complications, endangering maternal health and fetal development. The following chapter provides an overview of the structure and postimplantation morphogenesis of the definitive murine chorioallantoic placenta, including consideration of cell types and lineage. Furthermore, contemporary reagents and strategies for the analyses of placental phenotypes are highlighted.