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Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors
- Source :
- FEMS Microbiology Letters. 322:60-67
- Publication Year :
- 2011
- Publisher :
- Oxford University Press (OUP), 2011.
-
Abstract
- Staphylococcus lugdunensis is an opportunistic pathogen related to Staphylococcus aureus and Staphylococcus epidermidis. The genome sequence of S. lugdunensis strain N920143 has been compared with other staphylococci, and genes were identified that could promote survival of S. lugdunensis on human skin and pathogenesis of infections. Staphylococcus lugdunensis lacks virulence factors that characterize S. aureus and harbours a smaller number of genes encoding surface proteins. It is the only staphylococcal species other than S. aureus that possesses a locus encoding iron-regulated surface determinant (Isd) proteins involved in iron acquisition from haemoglobin.
- Subjects :
- 0303 health sciences
biology
030306 microbiology
Virulence
Staphylococcus lugdunensis
medicine.disease_cause
biology.organism_classification
Staphylococcal infections
medicine.disease
Microbiology
Genome
3. Good health
03 medical and health sciences
Staphylococcus aureus
Staphylococcus epidermidis
Genetics
medicine
Molecular Biology
Staphylococcus
Gene
030304 developmental biology
Subjects
Details
- ISSN :
- 03781097
- Volume :
- 322
- Database :
- OpenAIRE
- Journal :
- FEMS Microbiology Letters
- Accession number :
- edsair.doi...........3d44ece5ba51f3d7415e36c569fbc6d9