AB1377 Is the patient global health assessment reliable in juvenile idiopathic arthritis (JIA)?

Background JIA is a chronic autoimmune disease that poses many challenges. There is increasing recognition of the importance of patient-reported outcomes (PROs) and newer PROs are being developed and more widely utilised both in clinical care and in research, However, their performance and reliability remain unclear. Objectives This study seeks to evaluate: 1 performance of the patient global health assessment (PGA) compared to standard disease activity measures in children with JIA, 2 correlations of the PGA with socioeconomic status (SES) in JIA, and 3 relationship between PGA and physician global health assessment in JIA. Methods A convenience sample of patients with JIA (n=47) aged 2–18 were recruited from a single centre. Patients aged ≥10 years completed the questionnaire, and parents of patients aged 2–9 completed a proxy questionnaire for their child. Correlations between 1 the PGA and disease activity, as measured by the Juvenile Disease Activity Score-71 (JADAS-71), 2 the PGA and physician global health assessment, and 3 the physician global health assessment and the JADAS-71 were evaluated using Spearman correlation coefficients. PGAs were compared by age, sex, insurance status, race, and ethnicity; and differences between PGA and physician global health assessments were compared using Wilcoxon rank-sum tests. Results 16 parents and 31 patients completed the assessments (table 1). There was a moderate correlation between PGA and JADAS-71 (r=0.503, p Conclusions Our results demonstrate that physician global health assessment had a stronger correlation with standard disease activity measures than the PGA. These scores were higher in patients who were non-White race, Hispanic, and had Medicaid insurance; however, these were not statistically significant. These data indicate that the PGA is fairly stable across groups, and can be used reliably for disease monitoring. Disclosure of Interest None declared