Preparation of optically active aziridine carboxylates by lipase-catalyzed alcoholysis

Authors :: Alain Méou
Monique Martres
G. Gil
Source :: Tetrahedron Letters. 35:8787-8790
Publication Year :: 1994
Publisher :: Elsevier BV, 1994.
Abstract: Aziridine carboxylates alcoholysis by lipases depends of the N-substituent. N-alkyl and N-aryl compounds have been resolved with medium to good enantiomeric purity by enzymatic alcoholysis catalyzed by pig pancreatic (PPL) or Candida cylindracea lipase (CCL).

Subjects :: chemistry.chemical_classification
biology
Chemistry
Organic Chemistry
Optically active
Aziridine
Biochemistry
Candida cylindracea
Catalysis
chemistry.chemical_compound
Enzyme
Drug Discovery
biology.protein
Organic chemistry
Enantiomer
Lipase

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