493 Preclinical pharmacokinetic (PK)/pharmacodynamic (PD)/Efficacy modeling for MLN2480, an investigational pan-RAF kinase inhibitor, in A375 and SKMEL-2 human melanoma xenografts

Authors :: J. Mettetal
W.C. Shyu
S. Balani
P. Shimoga
C.J. Zopf
Arijit Chakravarty
J. Chouitar
E. Gangolli
K. Galvin
Manish R. Patel
Source :: European Journal of Cancer. 50:161
Publication Year :: 2014
Publisher :: Elsevier BV, 2014.

Subjects :: Cancer Research
Oncology
Pharmacokinetics
business.industry
Pharmacodynamics
Medicine
Human melanoma
Raf Kinase Inhibitor
Pharmacology
business

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