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Isoniazid pharmacokinetics in children treated for respiratory tuberculosis
- Source :
- Archives of Disease in Childhood. 90:614-618
- Publication Year :
- 2005
- Publisher :
- BMJ, 2005.
-
Abstract
- Aims: To define the pharmacokinetics of isoniazid (INH) in children with tuberculosis in relation to the N-acetyltransferase 2 (NAT2) genotype. Methods: The first order elimination rate constant (k) and area under the concentration curve (AUC) were calculated in 64 children
- Subjects :
- medicine.medical_specialty
business.industry
Isoniazid
Area under the curve
Gastroenterology
Pharmacokinetics
Elimination rate constant
Internal medicine
Pediatrics, Perinatology and Child Health
Genotype
Immunology
Medicine
Analysis of variance
business
Pharmacogenetics
Antibacterial agent
medicine.drug
Subjects
Details
- ISSN :
- 14682044 and 00039888
- Volume :
- 90
- Database :
- OpenAIRE
- Journal :
- Archives of Disease in Childhood
- Accession number :
- edsair.doi...........3b77292aaf37743c39fec082acab598a
- Full Text :
- https://doi.org/10.1136/adc.2004.052175