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Age influence on mice lung tissue response to Aspergillus fumigatus chronic exposure
- Source :
- Annals of Agricultural and Environmental Medicine. 22:69-75
- Publication Year :
- 2015
- Publisher :
- Institute of Rural Health, 2015.
-
Abstract
- Exposure to conidia of Aspergillus fumigatus was described as a causative factor of a number of the respiratory system diseases, including asthma, chronic eosinophilic pneumonia, hypersensitivity pneumonitis and bronchopulmonary aspergillosis. The study investigates the effects of the repeated exposure to A. fumigatus in mice pulmonary compartment. Our work tackles two, so far insufficiently addressed, important aspects of interaction between affected organism and A. fumigatus: 1) recurrent character of exposure (characteristic for pathomechanism of the abovementioned disease states) and 2) impact of aging, potentially important for the differentiation response to an antigen.
- Subjects :
- Chronic exposure
Public Health, Environmental and Occupational Health
Disease
Biology
biology.organism_classification
medicine.disease
Aspergillus fumigatus
Antigen
Immunology
medicine
Respiratory system
skin and connective tissue diseases
Lung tissue
Waste Management and Disposal
Ecology, Evolution, Behavior and Systematics
Hypersensitivity pneumonitis
Asthma
Subjects
Details
- ISSN :
- 18982263 and 12321966
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Annals of Agricultural and Environmental Medicine
- Accession number :
- edsair.doi...........3b212028b5900c330b26797b6413669c