Glycemic Control and Interleukin-1beta in Periodontal Patients with Type 1 and 2 Diabetes in a Group of Subjects in South-West Romania

Interleukin-1b is an important mediator of the inflammatory response and is involved in the pathophysiology of periodontitis. The purpose of the study was to investigate the influence of periodontal disease and glycemic control on biomarker levels in crevicular fluid. Patients with aggressive periodontitis were characterized by a higher ratio of IL-1b compared to patients with chronic periodontitis.