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ChemInform Abstract: Synthesis of Protected α-Alkyl Lanthionine Derivatives
- Source :
- ChemInform. 45
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- Protected α-alkyl lanthionine derivatives were synthesized in five steps starting from a known phenyloxazoline precursor. This approach involved the synthesis of a family of substituted cyclic sulfamidates and their regioselective opening by nucleophilic attack with a protected cysteine. This efficient multistep strategy affords various α-alkylated lanthionine derivatives in high yields.
Details
- ISSN :
- 09317597
- Volume :
- 45
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........3a38dcbfbffab5ea51a35f302d01fb40