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Nano-composite of Co3O4 and Cu with enhanced stability and catalytic performance for non-enzymatic electrochemical glucose sensors
- Source :
- RSC Advances. 7:54460-54467
- Publication Year :
- 2017
- Publisher :
- Royal Society of Chemistry (RSC), 2017.
-
Abstract
- Nanostructured Co3O4 with near-cubic morphology was synthesised using the solvothermal method, and a non-enzymatic electrochemical glucose sensor (Co3O4–CuNPs/Pt) was successfully constructed by dropping and potentiostatic depositing technologies. The obtained Co3O4 and Co3O4–CuNPs were characterised and investigated by X-ray powder diffraction, scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray spectroscopy and X-ray photoelectron spectroscopy. Quantitative analysis of glucose was performed using the amperometric (i–t) method, and a plot of current difference versus concentration of glucose was linear in the range 0.5–336 μM, with a linear correlation coefficient (R2) of 0.9989 and limit of detection (LOD) of 0.43 μM. When the linear range was reduced to 0.5–76.5 μM, R2 and LOD were 0.9997 and 0.17 μM, respectively. The sensitivity of the sensor was evaluated as 3.58 × 104 and 4.03 × 104 μA μM−1 cm−2 for the above two linear ranges, respectively. This novel sensor produced satisfactory reproducibility and stability and was applied to monitor trace amounts of glucose in human serum samples.
- Subjects :
- Detection limit
Materials science
Scanning electron microscope
General Chemical Engineering
Analytical chemistry
02 engineering and technology
General Chemistry
010402 general chemistry
021001 nanoscience & nanotechnology
01 natural sciences
Amperometry
0104 chemical sciences
Linear range
X-ray photoelectron spectroscopy
Transmission electron microscopy
0210 nano-technology
Spectroscopy
Powder diffraction
Subjects
Details
- ISSN :
- 20462069
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- RSC Advances
- Accession number :
- edsair.doi...........394b6aa96ae2bef700803140373f44ce