First Detection of NDM-5-Positive Salmonella enterica Serovar Typhimurium Isolated from Retail Pork in China

In this study, a carbapenem-resistant Salmonella enterica serovar Typhimurium strain W131 (sequence type 34) was isolated from retail pork in Jiangsu province, China. An IncX3 plasmid carrying blaNDM-5 element was identified in this strain by whole-genome sequencing analysis. The conjugation experiment demonstrated that the plasmid can be transferred to Escherichia coli recipient J53 and conferred carbapenem resistance to the recipient strain. This study first reported a Salmonella Typhimurium strain with blaNDM-5 from retail pork, which revealed that retail meat as a potential transmission factor of carbapenem-resistant blaNDM-5 to be a threat human health.