Hyperghrelinemia in the patients presenting with Prader-Willi syndrome

The present study was designed to measure pre- and postprandial ghrelin secretion in the children presenting with Prader-Willi syndrome (PWS). The clinical, hormonal, and metabolic characteristics of 17 prepubertal children with the genetically verified diagnosis of PWS, 15 patients with exogenous-constitutional obesity, and 10 healthy children are presented. The children suffering PWS were found to exhibit pre- and postprandial hyperghrelinemia.