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PO-032 The protective effects of curcumin on exercise-induced renal ischemia reperfusion injury in rats

Authors :
Hai-Tao Zhou
Yan-Long Niu
Jian-Min Cao
Fang Li
Source :
Exercise Biochemistry Review. 1
Publication Year :
2018
Publisher :
Universite Catholique de Louvain, 2018.

Abstract

Objective This study was designed to investigate the effects of curcumin on inflammatory factors and ECM expression in exercise-induced renal ischemia reperfusion injury in rats. Methods Sixty 7-week-old male SD rats were divided randomly into three groups: group A (normal control group, n=12), group B (overtraining group, n=24) and group C (curcumin + overtraining group, n=24). Group B and C performed 6 weeks of incremental load training on the treadmill. 24 hours after the last training, the rats were anesthetized intraperitoneally, the morphology of renal tissue and the deposition of glomerular ECM were observed using light microscope,the related biochemical indexes were tested. Results (1) the renal structure of rats in group A were normal, histopathological changes were observed in group B and C, Paller score of group B were significantly higher than group A(P

Details

ISSN :
25937588
Volume :
1
Database :
OpenAIRE
Journal :
Exercise Biochemistry Review
Accession number :
edsair.doi...........3817ffb1e3d29893283e15b576922680
Full Text :
https://doi.org/10.14428/ebr.v1i3.9973