Ultrasensitive surface refractive index imaging in all-dielectric structures

A novel hyperspectral sensing imaging taking advantage of engineered all-dielectric metasurfaces supporting bound states in the continuum here is discussed. This approach combines surface-enhanced fluorescence and res- onant shift both based on high-Q resonances in proximity of bound states in the continuum. The amplification of the optical field on resonance allows increasing the fluorescence emission of a dye as a function of the spatial- variant dielectric environment in the near-field of the structure. We first demonstrate the fluorescence emission amplification by resonant pump matching in microscopy configuration. Then, we take advantage of Fano reso- nances in the fluorescence emission to map the spatially variant environment of biological cells. To demonstrate the real implementation of the proposed BIC-enhanced imaging as a platform for biosensing, hyperspectral maps of prostate cancer cells are experimentally reconstructed.