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Percutaneous absorption of azidothymidine in rats
- Source :
- International Journal of Pharmaceutics. 57:73-75
- Publication Year :
- 1989
- Publisher :
- Elsevier BV, 1989.
-
Abstract
- Percutaneous absorption of azidothymidine (AZT) was examined in rats. When AZT was applied as a solution in 10% oleic acid/water on the abdominal skin which had been treated with 10% oleic acid/water for 24 h, considerable plasma concentrations of AZT were observed.
- Subjects :
- Abdominal skin
viruses
virus diseases
Pharmaceutical Science
Absorption (skin)
biochemical phenomena, metabolism, and nutrition
Pharmacology
Oleic acid
chemistry.chemical_compound
Zidovudine
chemistry
Biochemistry
Pharmacokinetics
immune system diseases
Oral administration
Percutaneous absorption
Plasma concentration
medicine
heterocyclic compounds
medicine.drug
Subjects
Details
- ISSN :
- 03785173
- Volume :
- 57
- Database :
- OpenAIRE
- Journal :
- International Journal of Pharmaceutics
- Accession number :
- edsair.doi...........37bbcd5562b883dc46b32d17d45092a2
- Full Text :
- https://doi.org/10.1016/0378-5173(89)90265-2