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Pilot trial of an Indoleamine 2,3-dioxygenase-1 (IDO1) inhibitor plus a multipeptide melanoma vaccine in patients with advanced melanoma
- Source :
- Journal of Clinical Oncology. 36:3033-3033
- Publication Year :
- 2018
- Publisher :
- American Society of Clinical Oncology (ASCO), 2018.
-
Abstract
- 3033Background: Melanoma metastases limit infiltration and function of antitumor T cells in part by immunosuppression with IDO1. INCB024360 (epacadostat) is an IDO1 inhibitor that normalizes serum ...
- Subjects :
- 0301 basic medicine
Cancer Research
business.industry
medicine.medical_treatment
Melanoma
Pilot trial
Immunosuppression
medicine.disease
Melanoma Vaccine
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Oncology
030220 oncology & carcinogenesis
medicine
Cancer research
In patient
Indoleamine 2,3-dioxygenase
business
Infiltration (medical)
Advanced melanoma
Subjects
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 36
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi...........36c0e195a11e99f3403e9f4cca163366