The Cellular Basis of RE Stimulation: The Effects on Peritoneal Cells of Stimulation with Glyceryl Trioleate, Studied by EM and Autoradiography

Among the many substances that stimulate reticuloendothelial function, one of the most convenient experimentally is glyceryl trioleate [1]. This substance has been shown to have an effect on individual RE cells. After exposure to it in vitro a population of peritoneal cells had increased phagocytic activity toward bacteria [2], probably due to an increase in the number of active cells [3]. The cellular mechanism of this effect is obscure.