Synthesis and Spectral Analysis of New Antitumor Compounds with Benzimidazole Structure

Amidic compounds, derivatives of the 5-nitro-benzimidazolyl-2-mercapto-acetic acid were obtained in order to get new cytostatic substances. Two azotyperitic derivatives were obtained by the grafting of the di-(b-chloroethyl)-amine group on molecules of two of the amidic compounds. The NMR and FT-IR spectra confirmed the structure of the new compounds. The mitodepresive action of the new compounds has been tested on root meristems of Lepidiumm sativum L.