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ChemInform Abstract: Microwave-Assisted Copper-Free Sonogashira Coupling/5-exo-Dig Cycloisomerization Domino Reaction: Access to 3-(Phenylmethylene)isoindolin-1-ones and Related Heterocycles

Authors :
Gregory D. Cuny
Malik Hellal
Source :
ChemInform. 43
Publication Year :
2012
Publisher :
Wiley, 2012.

Abstract

An efficient microwave assisted one-pot synthesis of substituted 3-(phenylmethylene)isoindolin-1-ones is reported via a copper-free Sonogashira coupling and a regioselective 5-exo-dig cycloisomerization. This domino reaction was also extended to other related heterocycles.

Details

ISSN :
09317597
Volume :
43
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........358c25a57e6a6671f7f170fb7489908f
Full Text :
https://doi.org/10.1002/chin.201205125