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Growth hormone replacement therapy improves hypopituitarism-associated hypoxemia in a patient after craniopharyngioma surgery
- Source :
- Medicine. 98:e14101
- Publication Year :
- 2019
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2019.
-
Abstract
- Rationale There are some reports about hypoxemia related to hypopituitarism. However, little is known about the relationship between growth hormone deficiency (GHD) and hypoxemia. Patients concerns A 23-year-old female presented with severe hypoxemia after the operations of craniopharyngioma. Laboratory tests found that serum growth hormone (GH) levels were extremely low. Diagnosis She was diagnosed with growth hormone deficiency-related hypoxemia. Interventions In addition to oxygenation, low doses of GH replacement therapy was conducted for 3-month. Outcomes After 3-month r-hGH replacement therapy, hypoxemia was improved significantly and the level of serum GH was elevated. Lessons We've already known that hypopituitarism may induce hypoxemia owing to multiple possible mechanisms according to previous literature. But little is known about growth hormone deficiency-related hypoxemia. Our case shows that GH replacement therapy is an effective treatment, and it's significant to examination the level of GH in serum for hypoxemia patients especially when the cause of hypoxemia is unknown.
- Subjects :
- Pediatrics
medicine.medical_specialty
business.industry
Serum growth hormone
General Medicine
Hypopituitarism
Oxygenation
Growth hormone
medicine.disease
Craniopharyngioma
respiratory tract diseases
Hypoxemia
Growth hormone deficiency
03 medical and health sciences
0302 clinical medicine
030220 oncology & carcinogenesis
medicine
030212 general & internal medicine
Young adult
medicine.symptom
business
circulatory and respiratory physiology
Subjects
Details
- ISSN :
- 15365964 and 00257974
- Volume :
- 98
- Database :
- OpenAIRE
- Journal :
- Medicine
- Accession number :
- edsair.doi...........3544f78ccf251f532806b314759d66b4