Pyridoxal-derived Schiff’s bases

Over the past few decades synthesis of functionalized derivatives of pyridoxal (vitamin B6) and study of their biological activity have received a great deal of interest [1–3]. Among these compounds, monoand bis-azomethines of pyridoxal occupy an important place [4–6]. In practice, pyridoxal hydrochloride is often used since free pyridoxal is unstable and undergoes irreversible fast transformation.