Back to Search Start Over

Effects of aging on coronary flow reserve in patients with no evidence of myocardial perfusion abnormality

Authors :
Yasuki Kihara
Kazuhiro Nitta
Hiroto Utsunomiya
Yukihiro Fukuda
E Ramandika
Ken Ishibashi
Hiroki Ikenaga
Takayuki Hidaka
Satoshi Kurisu
Source :
European Heart Journal. 41
Publication Year :
2020
Publisher :
Oxford University Press (OUP), 2020.

Abstract

Background Coronary flow reserve (CFR) reflects the functional capacity of microcirculation to adapt to blood demand during increased cardiac work. Purpose We tested the hypothesis that aging had impacts on coronary flow velocities and CFR in patients with no evidence of myocardial perfusion abnormality on single photon emission computed tomography (SPECT). Methods and results Seventy-six patients with no evidence of myocardial perfusion abnormality on SPECT undergoing transthoracic Doppler echocardiography were enrolled in this study. Patients were divided into three age groups: 17 patients aged Conclusions Our data suggested that aging impaired CFR in patients with no evidence of myocardial perfusion abnormality primarily due to the decrease in hyperemic coronary flow velocity. Comparison of coronary flow reserve amon Funding Acknowledgement Type of funding source: None

Details

ISSN :
15229645 and 0195668X
Volume :
41
Database :
OpenAIRE
Journal :
European Heart Journal
Accession number :
edsair.doi...........3420797f0a784d20e36ae27f51b9498b