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Effects of aging on coronary flow reserve in patients with no evidence of myocardial perfusion abnormality
- Source :
- European Heart Journal. 41
- Publication Year :
- 2020
- Publisher :
- Oxford University Press (OUP), 2020.
-
Abstract
- Background Coronary flow reserve (CFR) reflects the functional capacity of microcirculation to adapt to blood demand during increased cardiac work. Purpose We tested the hypothesis that aging had impacts on coronary flow velocities and CFR in patients with no evidence of myocardial perfusion abnormality on single photon emission computed tomography (SPECT). Methods and results Seventy-six patients with no evidence of myocardial perfusion abnormality on SPECT undergoing transthoracic Doppler echocardiography were enrolled in this study. Patients were divided into three age groups: 17 patients aged Conclusions Our data suggested that aging impaired CFR in patients with no evidence of myocardial perfusion abnormality primarily due to the decrease in hyperemic coronary flow velocity. Comparison of coronary flow reserve amon Funding Acknowledgement Type of funding source: None
- Subjects :
- medicine.medical_specialty
medicine.diagnostic_test
business.industry
Coronary flow reserve
Doppler echocardiography
Perfusion abnormality
Single-photon emission computed tomography
medicine.disease
Microcirculation
Cigarette smoking
Internal medicine
Diabetes mellitus
medicine
Cardiology
In patient
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 15229645 and 0195668X
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- European Heart Journal
- Accession number :
- edsair.doi...........3420797f0a784d20e36ae27f51b9498b