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ChemInform Abstract: Silver-Catalyzed Double-Decarboxylative Cross-Coupling of α-Keto Acids with Cinnamic Acids in Water: A Strategy for the Preparation of Chalcones
- Source :
- ChemInform. 46
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- A silver-catalyzed double-decarboxylative protocol has been proposed for the construction of chalcone derivatives via cascade coupling of substituted α-keto acids with cinnamic acids under the mild aqueous conditions. The developed method for constructing C-C bonds via double-decarboxylative reactions is efficient, practical, and environmentally benign by using the readily available starting materials. It should provide a promising synthesis candidate for the formation of diverse and useful chalcone derivatives in the fields of synthetic and pharmaceutical chemistry.
Details
- ISSN :
- 09317597
- Volume :
- 46
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........33c34a517d5015b099e215b22ee3c85f