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A case of IgG4-related chronic sclerosing sialadenitis associated with autoimmune pancreatitis
- Source :
- Japanese Journal of Oral & Maxillofacial Surgery. 54:558-562
- Publication Year :
- 2008
- Publisher :
- Japanese Society of Oral and Maxillofacial Surgeons, 2008.
-
Abstract
- A 77-year-old man with a painless and bilateral submandibular swelling was referred to our hospital. He had already been treated with systemic prednisolone for retrobulbar neuritis. Laboratory examinations showed high serum IgG4 concentrations, and a biopsy of the submandibular gland revealed the infiltration of IgG4-positive plasmacytes. Abdominal CT demonstrated tumor formation in the tail of the pancreas. These findings suggested the patient to have Mikulicz's disease associated with localized autoimmune pancreatitis. Treatment with prednisolone improved the swelling of the submandibular gland. As a result, when a paticent is suspected to have Mikulicz's disease, it is important to consider the possibility of systemic IgG4-related plasmacytic disease.
- Subjects :
- Pathology
medicine.medical_specialty
medicine.diagnostic_test
business.industry
Chronic sclerosing sialadenitis
Neuritis
medicine.disease
Submandibular gland
medicine.anatomical_structure
stomatognathic system
parasitic diseases
Biopsy
medicine
Prednisolone
Pancreas
business
Infiltration (medical)
Autoimmune pancreatitis
medicine.drug
Subjects
Details
- ISSN :
- 21861579 and 00215163
- Volume :
- 54
- Database :
- OpenAIRE
- Journal :
- Japanese Journal of Oral & Maxillofacial Surgery
- Accession number :
- edsair.doi...........336b02c667c0d2ebdb036afb6cbeede0