Variants of concern are overrepresented among post-vaccination breakthrough infections of SARS-CoV-2 in Washington State

Authors :: Meei-Li Huang
Shah A Mohamed Bakhash
Vanessa A. Makarewicz
Robert J. Livingston
Steven A. Pergam
Estella Whimbey
Pavitra Roychoudhury
Kathy Strand
Adrienne Schippers
Seth M. Cohen
Nandita S Mani
Elizabeth R. Brown
Noah R. Baker
Allison J Zellikoff
Catherine Liu
Abbye E McEwen
John B. Lynch
Jared Castor
Alexander L. Greninger
Keith R. Jerome
Chloe Bryson-Cahn
Publication Year :: 2021
Publisher :: Cold Spring Harbor Laboratory, 2021.
Abstract: Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOC) and had a median Ct of 20.2 (IQR=17.1-23.3). When compared to 5174 contemporaneous samples sequenced in our laboratory, VOC were significantly enriched among breakthrough infections (p < .05).

Subjects :: 2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19)
business.industry
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Post vaccination
Medicine
business
Virology

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