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An Efficient Synthesis of Dimemorfan from Dextromethorphan

Authors :
Xiu-Lian Ju
Ou Xianfei
Zheng Wenyue
Hui Liu
Source :
Organic Preparations and Procedures International. 47:214-219
Publication Year :
2015
Publisher :
Informa UK Limited, 2015.

Abstract

Dimemorfan [(+)-3-methyl-N-methylmorphinan, DF], widely used as an antitussive drug without narcotic effects,1,2 is an analogue of dextromethorphan [(+)-3-methoxy- N-methylmorphinan, DM]. However, ...

Details

ISSN :
19455453 and 00304948
Volume :
47
Database :
OpenAIRE
Journal :
Organic Preparations and Procedures International
Accession number :
edsair.doi...........32a1944aacc684d8143ba5f35bc3e667