Novel, sensitive simplex and multiplex assays for KRAS and NRAS mutation detection

Authors :: Christina Andersen
Cristiana Sessa
Michael Boergesen
Stephen Hamilton-Dutoit
Samantha Epistolio
Luca Mazzucchelli
Mariann Guldmann-Christensen
Jan Lorenzen
Majbritt Hauge Kyneb
Kirsten Voogd
Milo Frattini
Alice Riva
Ulf Bech Christensen
Tine Yde Wolff
Source :: Journal of Clinical Oncology. 34:e23269-e23269
Publication Year :: 2016
Publisher :: American Society of Clinical Oncology (ASCO), 2016.
Abstract: e23269Background: Activating KRAS/NRAS mutations in colorectal cancer (CRC) predict resistance to anti Epidermal Growth Factor Receptor targeted therapies. To improve the molecular characterization...

Subjects :: Neuroblastoma RAS viral oncogene homolog
Cancer Research
integumentary system
Colorectal cancer
business.industry
medicine.disease
medicine.disease_cause
digestive system diseases
Oncology
Anti-Epidermal Growth Factor Receptor
medicine
Cancer research
Multiplex
Mutation detection
KRAS
business
neoplasms

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