Ovarian needle biopsy: A study of 84 cases with cytologic-histologic correlation

e16501 Background: Ovarian needle biopsy (ONB) is well tolerated and underutilized. It may be employed for preoperative diagnosis and to treat symptomatic benign cysts. There is reluctance to utilize this procedure due to potential cyst rupture or seeding of malignant cells. We studied the efficacy of ONB over an 11-year period at our institution. Methods: Between January 2000 and August 2012, we retrieved 134 ONB specimens from our database. One hundred sixteen (87%) were performed by obstetrician-gynecologists, 8 (6%) by radiologists, 4 (3%) by surgeons, and 6 (4%) by other clinicians. Results: Eighty-four (63%) cases had corresponding surgical specimens, 78 (93%) of which were obtained concomitantly. Ten (12%) cases were malignant and 74 (88%) benign (Table). Sensitivity and specificity of ONB were 70% and 100%, respectively. Forty-one (53%) were benign ovarian neoplasms, and 30 (39%) were cysts. Regarding malignant lesions, 8 (80%) were primary ovarian epithelial cancers. There was 1 granulosa cell tumor and 1 metastatic lung adenocarcinoma. Three false negative cases were noted; 2 serous borderline tumors and 1 mucinous cystadenocarcinoma. These were sampling errors; no diagnostic tumor cells were present in the aspirates. Conclusions: ONB may be effective in diagnosing and treating ovarian lesions. In our study, it was highly specific and sensitive, with the exception of borderline tumors. [Table: see text]