An innovative ultrasonic-assisted extraction process for enhancing the patchoulol from Pogostemon cablin essential oil using hydrotropes

Pogostemon cablin (Patchouli) is an aromatic herb cultivated for its high-value essential oil. It is majorly used as a base oil in fragrance formulation due to its characteristics sesquiterpenoid alcohols. Patchoulol is an imperative and bioactive sesquiterpenoid in the patchouli essential oil, which is primarily isolated from the aerial part of the plant. The patchoulol was enriched in this essential oil by ultrasonic-assisted extraction techniques using different hydrotropes viz., sodium p-toluene sulphonate, resorcinol, sodium cumene sulphonate and sodium salicylate. The effect of various parameters such as extraction time (min), ultrasonic amplitude (%) and pulse interval (s) with 2 M concentration of hydrotropes was studied. Ultrasonic assisted-techniques has improved the percentage of patchoulol in patchouli essential oil. The highest composition of patchoulol i.e., 70.06 % was obtained for 5 min extraction time, 40 % ultrasonic amplitude, 30:30 s pulse interval for sodium salicylate at 2 M concentration.