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The Role of Epigenetic Dysregulation in Suicidal Behaviors
- Source :
- Behavioral Neurobiology of Suicide and Self Harm ISBN: 9783030575731
- Publication Year :
- 2020
- Publisher :
- Springer International Publishing, 2020.
-
Abstract
- Suicidal behaviors have been associated with both heritable genetic variables and environmental risk factors. Epigenetic processes, such as DNA methylation, have important roles in mediating the effects of the environment on behavior. Dysregulation of these processes has been observed in many psychiatric disorders, and evidence suggests that they may also be involved in suicidal behaviors. Herein, we have summarized candidate gene and epigenome-wide studies which have investigated DNA methylation in relation to suicidal behaviors, as well as discussed some of the limitations of the field to date.
- Subjects :
- Genetics
03 medical and health sciences
Candidate gene
2019-20 coronavirus outbreak
0302 clinical medicine
Coronavirus disease 2019 (COVID-19)
Environmental risk
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
DNA methylation
Epigenetics
Psychology
030217 neurology & neurosurgery
030227 psychiatry
Subjects
Details
- ISBN :
- 978-3-030-57573-1
- ISBNs :
- 9783030575731
- Database :
- OpenAIRE
- Journal :
- Behavioral Neurobiology of Suicide and Self Harm ISBN: 9783030575731
- Accession number :
- edsair.doi...........2f953e8e420b949cae7573bc4a1daf83