Seliciclib (R-roscovitine) induces apoptosis in undifferentiated nasopharyngeal cancer (NPC) in vivo and in vitro

Authors :: Manuel Salto-Tellez
Y.-F. Lai
Simon Green
T. Loh
Ross A. Soo
Wen Son Hsieh
B.-K. Peh
C.-Y. Cui
Boon Cher Goh
B. Mow
Source :: Journal of Clinical Oncology. 23:3145-3145
Publication Year :: 2005
Publisher :: American Society of Clinical Oncology (ASCO), 2005.
Abstract: 3145 Cyclin dependent kinase (CDK) inhibition mimics tumor suppressor protein function and induces cell cycle arrest and apoptosis in cancer cell lines. Seliciclib, an orally administered inhibitor...

Subjects :: Cancer Research
Cell cycle checkpoint
Biology
In vitro
law.invention
chemistry.chemical_compound
Oncology
chemistry
Apoptosis
law
Cyclin-dependent kinase
In vivo
Cancer research
biology.protein
Suppressor
Seliciclib
Nasopharyngeal cancer

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