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Neoadjuvant Chemotherapy is Associated with Lower Lymph Node Counts in Colon Cancer
- Source :
- The American Surgeon. 84:996-1001
- Publication Year :
- 2018
- Publisher :
- SAGE Publications, 2018.
-
Abstract
- Adequate lymphadenectomy is associated with improved survival in patients who undergo oncologic resection of colorectal cancer and has been identified as a quality metric. Neoadjuvant chemotherapy has been found to be associated with collection of 12 lymph nodes. Of 9077 patients with a diagnosis of colon cancer who underwent colectomy, a minimum of 12 lymph nodes was harvested in 7897 (87%). Significant factors independently associated with inadequate lymphadenectomy included preoperative chemotherapy, emergent surgery, and T1 tumors (all P < 0.05). A large majority of patients who undergo colectomy for colon cancer have at least 12 lymph nodes collected. Preoperative chemotherapy is a major risk factor for inadequate lymph node retrieval. Recognition of factors associated with inadequate lymphadenectomy may improve colectomy lymph node yield and survival in patients with colon cancer.
- Subjects :
- medicine.medical_specialty
Chemotherapy
business.industry
Colorectal cancer
medicine.medical_treatment
General Medicine
medicine.disease
03 medical and health sciences
0302 clinical medicine
medicine.anatomical_structure
030220 oncology & carcinogenesis
medicine
030211 gastroenterology & hepatology
Lymphadenectomy
Radiology
Lymph
Risk factor
business
Lymph node
Neoadjuvant therapy
Colectomy
Subjects
Details
- ISSN :
- 15559823 and 00031348
- Volume :
- 84
- Database :
- OpenAIRE
- Journal :
- The American Surgeon
- Accession number :
- edsair.doi...........2f698bab53789d304d4027682761becf