Corticosteroid Therapy in Idiopathic Glomerulonephritis

Corticosteroids have multiple effects on the movement and functional capabilities of inflammatory or immunologically reactive cells, on various soluble factors, on vascular and tissue responses. There is a different sensitivity of various populations and sub-populations of cells to the corticosteroid modulation. These mechanisms are still under discussion, but the final effects appear to support the use of corticosteroids in certain patients with idiopathic glomerulonephritis (GN).