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In situ acyl triflates ace it

Authors :
Bill Morandi
Yong Ho Lee
Source :
Nature Chemistry. 10:116-117
Publication Year :
2018
Publisher :
Springer Science and Business Media LLC, 2018.

Abstract

A simple palladium catalyst has mediated the facile formation of aroyl triflates — an extremely reactive class of electrophiles. These intermediates, generated in situ, enable the Friedel–Crafts acylation of traditionally unreactive arenes, addressing a significant gap in C–H carbonylation methodology.

Details

ISSN :
17554349 and 17554330
Volume :
10
Database :
OpenAIRE
Journal :
Nature Chemistry
Accession number :
edsair.doi...........2eef74236a65f26d98393fff66669f74