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Intramolecular Diels–Alder synthesis of 7-aza-α-carboline compounds

Authors :
Phong H. Vu
Michael B. Wallace
Jeffrey A. Stafford
Jason W. Brown
Qing Dong
Nicholas Scorah
Source :
Tetrahedron Letters. 51:1739-1741
Publication Year :
2010
Publisher :
Elsevier BV, 2010.

Abstract

An efficient, versatile, and scalable route for the synthesis of 7-aza-α-carboline compounds is described. The tricyclic system has been prepared from modified pyrazinones using a key intramolecular [4+2] Diels–Alder transformation.

Subjects

Subjects :
chemistry.chemical_classification
chemistry
Stereochemistry
Intramolecular force
Organic Chemistry
Drug Discovery
Diels alder
Biochemistry
Tricyclic

Details

ISSN :
00404039
Volume :
51
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........2e5cb36ed8271c113520d5b9742698bb

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