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Can Tomosynthesis Solve the Problem of Mammographically Indeterminate Breast Lesions?
- Source :
- The Medical Journal of Cairo University. 87:2083-2098
- Publication Year :
- 2019
- Publisher :
- Egypts Presidential Specialized Council for Education and Scientific Research, 2019.
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Abstract
- Background: Breast cancer in women is a major public health problem throughout the world. To reduce the morbidity and mortality associated with breast cancer, early detection becomes a very important job. Addition of breast Tomosyn-thesis to mammography examination reduced and eliminated tissue overlap especially in women with radiographically dense breast.Aim of Study: To evaluate the impact of adding Digital Breast Tomosynthesis (DBT) to Full Field Digital Mammog-raphy (FFDM) in detection, characterization and diagnosis of mammographically indeterminate breast lesions.Subjects and Methods: The study included 80 patients with 86 indeterminate findings on mammography. DBT ex-amination was done and imaging findings were evaluated before and after the use of DBT.Results: Tomosynthesis showed better diagnostic perform-ance compared to mammography. The sensitivity of Tomo-synthesis was 90%, the specificity was 91.1%, the positive predictive value of 88%, the negative predictive value was 92.7% and the diagnostic accuracy was 91%, while the sensi-tivity of mammography was 62.5%, the specificity was 59%, the positive predictive value was 52.1%, the negative predictive value was 68.8%, and the diagnostic accuracy was 60.4%.Conclusion: DBT significantly enhanced the detection and characterization of indeterminate breast lesions on digital mammography especially in the context of dense breast parenchyma.
Details
- ISSN :
- 25369806
- Volume :
- 87
- Database :
- OpenAIRE
- Journal :
- The Medical Journal of Cairo University
- Accession number :
- edsair.doi...........2e1f7efd6ff582c890a3ca4e1e4f19fa