Valproate-coenzyme A conjugate blocks opening of receptor binding domains in the spike trimer of SARS-CoV-2 through an allosteric mechanism

Authors :: Federica Maschietto
Tianyin Qiu
Jimin Wang
Yuanjun Shi
Brandon Allen
George P. Lisi
Elias Lolis
Victor S. Batista
Source :: Computational and Structural Biotechnology Journal. 21:1066-1076
Publication Year :: 2023
Publisher :: Elsevier BV, 2023.

Subjects :: Structural Biology
Genetics
Biophysics
Biochemistry
Computer Science Applications
Biotechnology

Tools