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The current status of human laryngeal transplantation in 2017: A state of the field review
- Source :
- The Laryngoscope. 127:1861-1868
- Publication Year :
- 2017
- Publisher :
- Wiley, 2017.
-
Abstract
- Objectives Human laryngeal allotransplantation has long been contemplated as a surgical option following laryngectomy, but there is a paucity of information regarding the indications, surgical procedure, and patient outcomes. Our objectives were to identify all human laryngeal allotransplants that have been undertaken and reported in the English literature and to evaluate the success of the procedure. Data Sources MEDLINE, Embase, Current Index to Nursing and Allied Health Literature, Web of Science and Scopus, and the Gray literature. Review Methods A comprehensive search strategy was undertaken across multiple databases. Inclusion criteria were case reports of patients who had undergone human laryngeal allotransplantation. Information regarding indications, operative techniques, complications, graft viability, and functional outcomes were extracted. Results A total of 5,961 articles, following removal of duplicates, matched the search criteria and were screened, with five case reports relating to two patients, ultimately fulfilling the entry criteria. Conclusions Two laryngeal transplants have been reported in the medical literature. Although both patients report improved quality of life relating to their ability to communicate with voice, further research is necessary to shape our understanding of this complicated operation, its indications, and its functional outcomes. Laryngoscope, 127:1861–1868, 2017
- Subjects :
- Larynx
medicine.medical_specialty
business.industry
medicine.medical_treatment
Scopus
MEDLINE
Surgery
Laryngectomy
Transplantation
03 medical and health sciences
0302 clinical medicine
medicine.anatomical_structure
Otorhinolaryngology
Quality of life
030220 oncology & carcinogenesis
Medicine
030223 otorhinolaryngology
business
Intensive care medicine
Medical literature
Allotransplantation
Subjects
Details
- ISSN :
- 0023852X
- Volume :
- 127
- Database :
- OpenAIRE
- Journal :
- The Laryngoscope
- Accession number :
- edsair.doi...........2da17b31bec5daa4dff5812503f29d61