Upconversion Luminescent Chemodosimeter Based on NIR Organic Dye for Monitoring Methylmercury In Vivo

Mercury is one of the most hazardous and ubiquitous heavy metals, which may accumulate in human body through the food chain. [ 1 ] It shows high permeability into skin, respiratory and gastrointestinal systems of the human body, and can cause serious damage to the central nervous system. [ 2 ] Therefore, it is very important to develop various methods to effi ciently detect mercury in vitro and in vivo. Luminescence bioimaging provides an important means of visualizing morphological details of tissues with subcellular resolution and has become a powerful tool for manipulation in the biological analysis and medical diagnosis and treatment. [ 3 ]