Function of the Infrapatellar Fat Pad and Advanced Hoffa's Disease With Ossification

©2014 Turkish League Against Rheumatism. All rights reserved. Hoffa’s disease (or Hoffa’s fat pad syndrome) is a clinical condition, which develops as a result of impingement of the infrapatellar fat pad (IFP) between the femorotibial and femoropatellar spaces after inflammation and edema, and may cause knee pain.1 It generally begins with trauma at early ages. This condition can be confused with frequent meniscal pathologies of the knee joint. The infrapatellar fat pad is one of the three pads located on the anterior knee together with quadriceps and prefemoral fat pads.2 It is a tissue with known biomechanical functions. However, its endocrine functions are not fully understood.3